The Anti-PPM1G Antibody (CAB20959) is a valuable tool for researchers studying PPM1G, a protein phosphatase involved in various cellular processes such as cell cycle regulation and stress responses. This polyclonal antibody, developed in rabbits, exhibits high specificity and sensitivity in detecting PPM1G in human samples, making it suitable for use in Western blotting and immunohistochemistry studies.PPM1G, also known as protein phosphatase Mg2+/Mn2+ dependent 1G, plays a crucial role in dephosphorylating target proteins and regulating their activity.
Dysregulation of PPM1G has been implicated in several diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. By targeting PPM1G with this antibody, researchers can gain insights into its functions and potential therapeutic implications in these disease contexts.Overall, the Anti-PPM1G Antibody (CAB20959) offers a reliable tool for investigating the role of PPM1G in cellular processes and disease pathogenesis, providing valuable data for furthering research in cell biology and therapeutic development.
Product Name:
PPM1G Monoclonal Antibody
SKU:
CAB20959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 301-450 of human PPM1G (O15355).
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
Purification Method:
Affinity purification
Gene ID:
5496
Clone Number:
ARC2947
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various lysates, using PPM1G antibody (CAB20959) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
