PPL Rabbit Polyclonal Antibody (CAB14051)
- SKU:
- CAB14051
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PPL Rabbit Polyclonal Antibody |
SKU: | CAB14051 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PPL (NP_002696.3). |
Sequence: | MNSL FRKR NKGK YSPT VQTR SISN KELS ELIE QLQK NADQ VEKN IVDT EAKM QSDL ARLQ EGRQ PEHR DVTL QKVL DSEK LLYV LEAD AAIA KHMK HPQG DMIA EDIR QLKE RVTN LRGK HKQI YRLA VK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:100 - 1:500 |
Synonyms: | PPL |
Positive Sample: | Mouse lung,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Mitochondrion, Nucleus, cytoskeleton, desmosome. |
Calculated MW: | 205kDa |
Observed MW: | 205kDa |
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
Purification Method: | Affinity purification |
Gene ID: | 5493 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |