The PPIH Polyclonal Antibody (CAB12172) is a valuable tool for researchers studying PPIH, a peptidyl-prolyl cis-trans isomerase involved in protein folding and chaperone activity. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for Western blot applications.PPIH is a critical protein in maintaining proper protein structure and function, making it essential for cellular processes such as protein folding and trafficking. Dysregulation of PPIH has been implicated in various diseases including cancer, neurodegenerative disorders, and viral infections.
Understanding the role of PPIH in these disease contexts is crucial for developing targeted therapies and interventions.With the PPIH Polyclonal Antibody, researchers can confidently detect and analyze PPIH expression in various cell types, providing valuable insights into its function and potential as a therapeutic target. This antibody is a valuable tool for studies in molecular biology, biochemistry, and drug development, offering reliable and accurate results for your research needs.
Product Name:
PPIH Rabbit Polyclonal Antibody
SKU:
CAB12172
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of human PPIH (NP_006338.1).
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
Purification Method:
Affinity purification
Gene ID:
10465
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPIH Rabbit pAb (CAB12172) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
