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PPIF Monoclonal Antibody [PAT1F5AT] (CPAB0147)

SKU:
CPAB0147
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1F5AT
Applications:
WB
ELISA
IHC
€149
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Description

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PPIF Monoclonal Antibody [PAT1F5AT] (CPAB0147)

The PPIF Polyclonal Antibody (CPAB0147) is a valuable tool for researchers studying the protein PPIF, also known as cyclophilin F, which plays a crucial role in mitochondrial function and cell death regulation. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.PPIF is a key regulator of the mitochondrial permeability transition pore (MPTP), which controls the flow of molecules in and out of the mitochondria and is involved in various cellular processes, including apoptosis and necrosis. Dysregulation of PPIF has been implicated in several diseases, making it a promising target for therapeutic interventions.

By using the PPIF Polyclonal Antibody, researchers can detect and analyze PPIF expression in different cell types, providing valuable insights into mitochondrial function and cell death pathways. This antibody is an essential tool for studies in mitochondrial biology, cell death mechanisms, and potential therapeutic strategies for diseases associated with mitochondrial dysfunction. Unlock the potential of your research with the PPIF Polyclonal Antibody.

Product Name:PPIF Antibody
Product Sku:CPAB0147
Size:5μg
Host Species:Mouse
Immunogen:Anti-human Cyclophilin-F mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Cyclophilin-F amino acids 3-27 purified from Ecoli.
Clone:PAT1F5AT.
Reactivity:Human
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:Cyclophilin-F antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:PPIF is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIF accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIF is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Synonyms:Oeptidylprolyl Isomerase F, PPIF, CYP-D, CYP3, SnuCyp-20, Peptidyl-prolyl cis-trans isomerase mitochondrial, Cyclophilin F, FLJ90798, MGC117207, peptidylprolyl isomerase F.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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