Cyclophilin B Rabbit Polyclonal Antibody (CAB7713)
The PPiB Polyclonal Antibody (CAB7713) is a valuable tool for researchers studying PPiB, a protein involved in various cellular processes such as protein folding and regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By targeting the PPiB protein, researchers can detect and analyze its expression in a variety of cell types, making it ideal for studies in biochemistry and cell biology.PPiB, also known as peptidylprolyl isomerase B, plays a crucial role in protein folding and conformational changes, making it a key player in maintaining cellular homeostasis.
Understanding the function and activity of PPiB is essential for unraveling its involvement in various cellular processes and diseases. By utilizing the PPiB Polyclonal Antibody, researchers can further explore the role of PPiB in health and disease, paving the way for potential therapeutic interventions targeting this vital protein.
Product Name:
Cyclophilin B Rabbit Polyclonal Antibody
SKU:
CAB7713
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 34-216 of human Cyclophilin B (NP_000933.1).
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Purification Method:
Affinity purification
Gene ID:
5479
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cyclophilin B antibody (CAB7713) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
