PPIAL4G Antibody (PACO29112)
- SKU:
- PACO29112
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PPIAL4G Antibody (PACO29112)
The PPIAL4G Polyclonal Antibody (PAC029112) is a valuable tool for researchers studying PPIAL4G, a protein involved in cellular processes such as protein folding and assembly. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the PPIAL4G protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and protein research.PPIAL4G is known for its role in protein quality control mechanisms, including chaperone-mediated protein folding and degradation pathways.
Understanding the function of PPIAL4G is important in unraveling the molecular mechanisms underlying protein homeostasis and cellular health. Research involving PPIAL4G may provide insights into various human diseases, including neurodegenerative disorders and cancer, where protein misfolding and aggregation are implicated.By utilizing the PPIAL4G Polyclonal Antibody in their experiments, scientists can further explore the functions and interactions of PPIAL4G, paving the way for advancements in drug discovery and therapeutic development targeting protein misfolding and aggregation-related diseases.
Antibody Name: | PPIAL4G Antibody (PACO29112) |
Antibody SKU: | PACO29112 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Peptidyl-prolyl cis-trans isomerase A-like 4G protein (1-164AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO29112 at dilution of 1:100. | |
Western Blot All lanes: PPIAL4G antibody at 6µg/ml Lane 1: Mouse liver tissue Lane 2: Mouse spleen tissue Lane 3: Mouse lung tissue Lane 4: Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 19 kDa Observed band size: 19 kDa . |
Background: | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
Synonyms: | Peptidyl-prolyl cis-trans isomerase A-like 4G (PPIase A-like 4G) (EC 5.2.1.8) (Peptidylprolyl cis-trans isomerase A-like 4), PPIAL4G |
UniProt Protein Function: | PPIAL4G: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.Protein type: EC 5.2.1.8; IsomeraseChromosomal Location of Human Ortholog: 1q21.1Cellular Component: cytoplasmMolecular Function: peptidyl-prolyl cis-trans isomerase activityBiological Process: protein folding; protein peptidyl-prolyl isomerization |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P0DN37 |
NCBI GenInfo Identifier: | 178057341 |
NCBI Gene ID: | 644591 |
NCBI Accession: | NP_001116540.1 |
UniProt Secondary Accession: | P0DN37,A1L431, A2BFH1 |
UniProt Related Accession: | P0DN37 |
Molecular Weight: | 18,166 Da |
NCBI Full Name: | peptidyl-prolyl cis-trans isomerase A-like 4G |
NCBI Synonym Full Names: | peptidylprolyl isomerase A like 4G |
NCBI Official Symbol: | PPIAL4GÂ Â |
NCBI Official Synonym Symbols: | COAS-2Â Â |
NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase A-like 4G |
UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase A-like 4G |
UniProt Synonym Protein Names: | Peptidylprolyl cis-trans isomerase A-like 4 |
Protein Family: | Peptidyl-prolyl cis-trans isomerase |
UniProt Gene Name: | PPIAL4GÂ Â |
UniProt Entry Name: | PAL4G_HUMAN |