The PPHLN1 Polyclonal Antibody (CAB17706) is a valuable tool for researchers studying PPHLN1, a protein involved in various cellular processes such as lipid metabolism and insulin resistance. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.PPHLN1, also known as Periphilin-1, is a key player in lipid droplet biogenesis and has been implicated in the development of metabolic disorders such as obesity and diabetes.
By targeting PPHLN1 with this antibody, researchers can gain insight into the role of this protein in these diseases and potentially identify new therapeutic strategies.With its specificity and reliability, the PPHLN1 Polyclonal Antibody is an essential tool for investigating the function and regulation of PPHLN1 in various cellular and disease contexts, making it an invaluable asset for researchers in the fields of metabolism, diabetes, and lipid biology.
Product Name:
PPHLN1 Rabbit Polyclonal Antibody
SKU:
CAB17706
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 195-255 of human PPHLN1 (NP_958846.1).
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
51535
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPHLN1 Rabbit pAb (CAB17706) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
