The PPFIBP2 Polyclonal Antibody (PACO39438) is a powerful tool for researchers studying PPFIBP2, a crucial protein involved in cell adhesion and signaling pathways. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blotting and immunofluorescence assays. By binding to the PPFIBP2 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it an essential tool for studies in cell biology and cancer research.PPFIBP2, also known as liprin-beta-1, plays a key role in cell migration, invasion, and adhesion processes, making it a promising target for understanding cancer metastasis and invasion mechanisms.
Its involvement in signaling pathways related to cytoskeleton regulation highlights its importance in various cellular functions. Research on PPFIBP2 is crucial for uncovering its role in cancer progression and its potential as a therapeutic target for cancer treatment.By using the PPFIBP2 Polyclonal Antibody, researchers can further explore the functions of PPFIBP2 in cellular processes and disease pathogenesis, ultimately leading to a better understanding of its potential implications in cancer biology and therapy development.
Antibody Name:
PPFIBP2 Antibody (PACO39438)
Antibody SKU:
PACO39438
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Recombinant Human Liprin-beta-2 protein (101-400AA)
Western blot. All lanes: PPFIBP2 antibody at 6µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 99, 87, 84 kDa. Observed band size: 99 kDa.
Background:
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Synonyms:
Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2), PPFIBP2
UniProt Protein Function:
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
