PPFIBP1 Rabbit Polyclonal Antibody (CAB16456)
- SKU:
- CAB16456
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PPFIBP1 Rabbit Polyclonal Antibody |
SKU: | CAB16456 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 846-1005 of human PPFIBP1 (NP_003613.3). |
Sequence: | LLNI PPNK TLLR RHLA THFN LLIG AEAQ HQKR DAME LPDY VLLT ATAK VKPK KLAF SNFG NLRK KKQE DGEE YVCP MELG QASG SASK KGFK PGLD MRLY EEDD LDRL EQME DSEG TVRQ IGAF SEGI NNLT HMLK EDDM FKDF AARS PSAS ITDE DSNV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | L2; SGT2; hSGT2; hSgt2p; NEDSMBA; PPFIBP1 |
Positive Sample: | A-375,HeLa,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, plasma membrane, presynaptic active zone |
Calculated MW: | 114kDa |
Observed MW: | 114kDa |
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 8496 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |