PPFIA1 Rabbit Polyclonal Antibody (CAB10388)
- SKU:
- CAB10388
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PPFIA1 Rabbit Polyclonal Antibody |
SKU: | CAB10388 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human PPFIA1 (NP_003617.1). |
Sequence: | IESR VGSG SLDN LGRF RSMS SIPP YPAS SLAS SSPP GSGR STPR RIPH SPAR EVDR LGVM TLLP PSRE EVRD DKTT IKCE TSPP SSPR ALRL DRLH KGAL HTVS HEDI RDIR NSTG SQDG PVSN PSSS NSSQ DSLH KAPK K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LIP1; LIP.1; LIPRIN; PPFIA1 |
Positive Sample: | U-87MG,293T,MCF7,DU145 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 136kDa |
Observed MW: | 136kDa |
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 8500 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |