PPEF1 Antibody (PACO29108)
- SKU:
- PACO29108
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
PPEF1 Antibody (PACO29108)
The PPEF1 Polyclonal Antibody (PAC029108) is a valuable tool for researchers studying PPEF1, a protein involved in cellular signaling and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the PPEF1 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in molecular biology and neuroscience.PPEF1, also known as protein phosphatase with EF-hand domain 1, is known to play a role in calcium signaling and neuronal function.
Its involvement in these processes makes it a target of interest for research on neurological disorders, such as Alzheimer's disease and Parkinson's disease. By understanding the function of PPEF1, researchers can gain insights into the mechanisms underlying these conditions and potentially develop new therapeutic strategies.
| Antibody Name: | PPEF1 Antibody (PACO29108) |
| Antibody SKU: | PACO29108 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Serine/threonine-protein phosphatase with EF-hands 1 protein (301-500AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: PPEF1 antibody at 1µg/ml Lane 1: U251 whole cell lysate Lane 2: A549 whole cell lysate Lane 3: Mouse gonadal tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 76, 70, 73, 45, 69 kDa Observed band size: 76 kDa . |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO29108 at dilution of 1:100. |
| Background: | May have a role in the recovery or adaptation response of photoreceptors. May have a role in development. |
| Synonyms: | Serine/threonine-protein phosphatase with EF-hands 1 (PPEF-1) (EC 3.1.3.16) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7), PPEF1, PPEF PPP7C |
| UniProt Protein Function: | PPEF-1: a Ser/Thr phosphatase. Contains at least two EF-hand calcium-binding motifs in its C terminus. May play a role in specific sensory neuron function and/or development. Shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced isoforms have been described.Protein type: EC 3.1.3.16; Protein phosphatase, dual-specificity; Motility/polarity/chemotaxis; Protein phosphatase, Ser/Thr (non-receptor)Chromosomal Location of Human Ortholog: Xp22Cellular Component: cytosolMolecular Function: protein binding; protein serine/threonine phosphatase activityBiological Process: protein amino acid dephosphorylation; regulation of rhodopsin mediated signaling |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14829 |
| NCBI GenInfo Identifier: | 12643541 |
| NCBI Gene ID: | 5475 |
| NCBI Accession: | O14829.1 |
| UniProt Secondary Accession: | O14829,O15253, Q9NU21, Q9UJH0, A6NHP4, A8K348 |
| UniProt Related Accession: | O14829 |
| Molecular Weight: | 68,806 Da |
| NCBI Full Name: | Serine/threonine-protein phosphatase with EF-hands 1 |
| NCBI Synonym Full Names: | protein phosphatase with EF-hand domain 1 |
| NCBI Official Symbol: | PPEF1Â Â |
| NCBI Official Synonym Symbols: | PP7; PPEF; PPP7C; PPP7CAÂ Â |
| NCBI Protein Information: | serine/threonine-protein phosphatase with EF-hands 1 |
| UniProt Protein Name: | Serine/threonine-protein phosphatase with EF-hands 1 |
| UniProt Synonym Protein Names: | Protein phosphatase with EF calcium-binding domain; PPEF; Serine/threonine-protein phosphatase 7; PP7 |
| Protein Family: | Serine/threonine-protein phosphatase |
| UniProt Gene Name: | PPEF1Â Â |
| UniProt Entry Name: | PPE1_HUMAN |
| Antibodies |
| PPEF1 Antibody (PACO11391) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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