PGC1 beta Rabbit Polyclonal Antibody (CAB17257)
- SKU:
- CAB17257
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PGC1 beta Rabbit Polyclonal Antibody |
SKU: | CAB17257 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 850-950 of human PGC1 beta (NP_001166170.1). |
Sequence: | SSRE LKRR FEVF GEIE ECEV LTRN RRGE KYGF ITYR CSEH AALS LTKG AALR KRNE PSFQ LSYG GLRH FCWP RYTD YDSN SEEA LPAS GKSK YEAM DFDS L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PERC; ERRL1; PGC1B; PGC-1(beta); PGC1 beta |
Positive Sample: | HeLa,MCF7,mouse brain |
Cellular Localization: | cytosol, mitochondrion, nucleoplasm, nucleus |
Calculated MW: | 113kDa |
Observed MW: | 113kDa |
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 133522 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |