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PPARGC1A Monoclonal Antibody [PAT25C8AT] (CPAB0674)

SKU:
CPAB0674
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a 
Clone:
PAT25C8AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

PPARGC1A Monoclonal Antibody [PAT25C8AT] (CPAB0674)

The PPARGC1A Polyclonal Antibody (CPAB0674) is a powerful tool for researchers studying the PPARGC1A protein, which is involved in regulating mitochondrial biogenesis and energy metabolism. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting applications. By targeting the PPARGC1A protein, researchers can accurately detect and analyze its expression levels in a variety of cell types, making it an essential tool for studies in metabolism, aging, and metabolic disorders.

PPARGC1A, also known as PGC-1α, is a key regulator of cellular energy metabolism and plays a critical role in modulating mitochondrial function and biogenesis. Its involvement in metabolic pathways makes it a promising target for research into metabolic diseases such as diabetes, obesity, and cardiovascular disorders. Understanding the function of PPARGC1A is essential for developing therapeutic strategies aimed at improving mitochondrial function and metabolic health in various disease contexts.

Product Name:PPARGC1A Antibody
Product Sku:CPAB0674
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PPARGC1A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPARGC1A protein 3-54 amino acids purified from Ecoli.
Clone:PAT25C8AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:PPARGC1A antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a 
Background:PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors which increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. PPARGC1A regulates main mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an important role in metabolic reprogramming in response to dietary availability through coordination of the expression of many genes participate in glucose and fatty acid metabolism. PPARGC1A induces the expression of PERM1 in the skeletal muscle and takes part in the integration of the circadian rhythms and energy metabolism.
Synonyms:Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, Ligand effect modulator 6, LEM6, PGC1, PGC1A, PPARGC1, PPARGC1A.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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