PPARD Rabbit Polyclonal Antibody (CAB5656)
- SKU:
- CAB5656
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PPARD Rabbit Polyclonal Antibody |
SKU: | CAB5656 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 102-361 of human PPARD (NP_803184.1). |
Sequence: | IRMK LEYE KCER SCKI QKKN RNKC QYCR FQKC LALG MSHN AIRF GRMP EAEK RKLV AGLT ANEG SQYN PQVA DLKA FSKH IYNA YLKN FNMT KKKA RSIL TGKA SHTA PFVI HDIE TLWQ AEKG LVWK QLVN GLPP YKEI SVHV FYRC QCTT VETV RELT EFAK SIPS FSSL FLND QVTL LKYG VHEA IFAM LASI VNKD GLLV ANGS GFVT REFL RSLR KPFS DIIE PKFE FAVK FNAL ELDD SDLA LFIA AIIL CGGE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB; PPARD |
Positive Sample: | Mouse liver,Mouse brain,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 50kDa |
Observed MW: | 54kDa |
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.
Purification Method: | Affinity purification |
Gene ID: | 5467 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |