The PPAR Gamma Rabbit Monoclonal Antibody (CAB19676) is a valuable tool for researchers studying Peroxisome proliferator-activated receptor gamma (PPAR gamma), a key regulator of adipogenesis, glucose metabolism, and inflammation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.PPAR gamma is a nuclear receptor that plays a crucial role in the regulation of lipid and glucose metabolism, making it a promising target for therapeutic interventions in metabolic disorders such as diabetes and obesity.
Additionally, PPAR gamma has been implicated in regulating inflammation and immune responses, highlighting its potential significance in diseases like cancer and autoimmune disorders.By using the PPAR Gamma Rabbit Monoclonal Antibody (CAB19676), researchers can accurately detect and analyze PPAR gamma expression in various cell types, providing insights into its role in physiological and pathological processes. This antibody is a valuable tool for further exploration of PPAR gamma function and the development of targeted therapies for metabolic and inflammatory diseases.
Product Name:
PPARγ Rabbit Monoclonal Antibody
SKU:
CAB19676
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PPARγ (P37231).
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
5468
Clone Number:
ARC0155
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPARγ antibody (CAB19676) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
