The PPAP2B Polyclonal Antibody (CAB15743) is a valuable tool for researchers studying the PPAP2B protein, also known as lipin-2. This antibody is produced in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. By binding specifically to the PPAP2B protein, this antibody enables the detection and analysis of PPAP2B in a variety of cell types.PPAP2B is a phosphatidate phosphatase enzyme that plays a crucial role in lipid metabolism and cell signaling. Dysregulation of PPAP2B has been implicated in various diseases, including metabolic disorders, neurodegenerative diseases, and cancer.
Understanding the function and expression of PPAP2B is essential for unraveling its role in these diseases and potentially identifying new therapeutic targets.By using the PPAP2B Polyclonal Antibody (CAB15743), researchers can gain valuable insights into the function and regulation of the PPAP2B protein, advancing our understanding of its role in health and disease. This antibody is a valuable tool for studies in fields such as lipid metabolism, cell signaling, and cancer research.
Product Name:
PPAP2B Rabbit Polyclonal Antibody
SKU:
CAB15743
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PPAP2B (NP_003704.3).
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells.
Purification Method:
Affinity purification
Gene ID:
8613
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PPAP2B antibody (CAB15743) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
