The PPAP2A Polyclonal Antibody (CAB3062) is a valuable tool for research involving PPAP2A, a phosphatase enzyme involved in lipid metabolism and cell signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting. By binding specifically to PPAP2A, this antibody allows for the detection and analysis of the enzyme in a wide range of cell types, making it an essential reagent for studies in lipid biology and signal transduction.PPAP2A plays a crucial role in lipid metabolism by catalyzing the dephosphorylation of phosphatidic acid, a key intermediate in lipid biosynthesis.
Dysregulation of PPAP2A activity has been implicated in various diseases, including cancer, metabolic disorders, and neurodegenerative conditions. Research into the function and regulation of PPAP2A is therefore instrumental in understanding these pathologies and developing targeted therapies to modulate lipid signaling pathways.Overall, the PPAP2A Polyclonal Antibody (CAB3062) offers researchers a reliable tool to investigate the role of PPAP2A in health and disease, providing valuable insights into the complex mechanisms underlying lipid metabolism and cell signaling processes.
Product Name:
PPAP2A Rabbit Polyclonal Antibody
SKU:
CAB3062
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PPAP2A (NP_003702.2).
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in synthesis of glycerolipids and in phospholipase D-mediated signal transduction. This enzyme is an integral membrane glycoprotein that plays a role in the hydrolysis and uptake of lipids from extracellular space. Alternate splicing results in multiple transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
8611
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPAP2A Rabbit pAb (CAB3062) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
