PPAN Rabbit Polyclonal Antibody (CAB7377)
- SKU:
- CAB7377
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PPAN Rabbit Polyclonal Antibody |
SKU: | CAB7377 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PPAN (NP_064615.3). |
Sequence: | MGQS GRSR HQKR ARAQ AQLR NLEA YAAN PHSF VFTR GCTG RNIR QLSL DVRR VMEP LTAS RLQV RKKN SLKD CVAV AGPL GVTH FLIL SKTE TNVY FKLM RLPG GPTL TFQV KKYS LVRD VVSS LRRH RMHE QQFA HPPL LVLN SFGP HGMH VKLM ATMF QNLF PSIN VHKV NLNT IKRC LLID YNPD SQEL DFRH YSIK VVPV GASR GMKK LLQE KFPN MSRL QDIS ELLA TGAG LSES EAEP DGDH NITE LPQA VAGR GNMR AQQS AVRL TEIG PRMT LQLI KVQE GVGE GKVM FHSF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SSF; SSF1; SSF2; BXDC3; SSF-1; PPAN |
Positive Sample: | U-87MG,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus. |
Calculated MW: | 53kDa |
Observed MW: | 53kDa/55kDa |
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
Purification Method: | Affinity purification |
Gene ID: | 56342 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |