The PPA1 Polyclonal Antibody (CAB2108) is a valuable tool for researchers studying PPA1, a critical enzyme involved in energy metabolism and cellular processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the PPA1 protein, allowing for accurate detection and analysis in various cell types.PPA1, also known as inorganic pyrophosphatase 1, plays a key role in maintaining cellular energy balance by catalyzing the hydrolysis of inorganic pyrophosphate.
Dysfunction of PPA1 has been implicated in various diseases, including cancer and metabolic disorders. Understanding the role of PPA1 in these pathological conditions is essential for developing targeted therapies and interventions.Overall, the PPA1 Polyclonal Antibody (CAB2108) is a powerful tool for researchers investigating the function and regulation of PPA1 in health and disease. Its high specificity and sensitivity make it a reliable choice for studies in biochemistry, metabolism, and cancer research.
Product Name:
PPA1 Rabbit Polyclonal Antibody
SKU:
CAB2108
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human PPA1 (NP_066952.1).
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme.
Purification Method:
Affinity purification
Gene ID:
5464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPA1 antibody (CAB2108) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.