PPA1 Monoclonal Antibody [PAT4G4AT] (CPAB0247)
- SKU:
- CPAB0247
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT4G4AT
- Applications:
- ELISA
- FC
Description
PPA1 Monoclonal Antibody [PAT4G4AT] (CPAB0247)
The PPA1 Polyclonal Antibody (CPAB0247) is a valuable tool for researchers studying PPA1, a key enzyme involved in the regulation of cellular metabolism and energy production. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PPA1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in biochemistry and cellular biology.PPA1, also known as inorganic pyrophosphatase 1, plays a critical role in cellular energy metabolism by catalyzing the hydrolysis of pyrophosphate, a key reaction in ATP synthesis.
Dysregulation of PPA1 activity has been linked to metabolic disorders and diseases such as cancer and neurodegenerative conditions. By gaining a deeper understanding of PPA1 function, researchers can uncover potential therapeutic targets for these complex diseases and develop innovative treatment strategies.Overall, the PPA1 Polyclonal Antibody (CPAB0247) offers researchers a powerful tool for exploring the intricate role of PPA1 in cellular metabolism and its implications for human health. Its specificity and reliability make it an essential component for studies aimed at unraveling the complexity of metabolic pathways and identifying novel targets for therapeutic intervention.
Product Name: | PPA1 Antibody |
Product Sku: | CPAB0247 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PPA1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPA1 protein 1-289 amino acids purified from Ecoli. |
Clone: | PAT4G4AT. |
Reactivity: | Human |
Applications: | ELISA, Flow Cytometry |
Purification Method: | PPA1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | PPA1 is a member of the PPase family. PPA1 catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. Many biochemical pathways use the hydrolysis of PPi to two phosphate ions to make the reactions permanently irreversible. A prominent illustration of this phenomenon is the inorganic pyrophosphatase catalyzation in the hydrolysis reaction at the beginning of lipid degradation. Inorganic pyrophosphatase provides the motivation for the activation of fatty acids destined for oxidation by stimulating the rapid hydrolysis of pyrophosphate. |
Synonyms: | Pyrophosphatase (inorganic) 1, PP, PP1, IOPPP, SID6-8061, Pyrophosphate phospho-hydrolase, PPase, cytosolic inorganic pyrophosphatase, diphosphate phosphohydrolase, inorganic diphosphatase, EC 3.6.1.1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |