PP2A-Aβ/PR65β/PPP2R1B Polyclonal Antibody (CAB24836)
- SKU:
- CAB24836
Description
| Product Name: | PP2A-Aβ/PR65β/PPP2R1B Polyclonal Antibody |
| SKU: | CAB24836 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 502-601 of human PP2A-Aβ/PR65β/PPP2R1B(NP_002707.3). |
| Sequence: | ANDP NYLH RMTT LFCI NALS EACG QEIT TKQM LPIV LKMA GDQV ANVR FNVA KSLQ KIGP ILDT NALQ GEVK PVLQ KLGQ DEDM DVKY FAQE AISV LALA |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | PPP2R1B; PP2A-Abeta; PR65B; protein phosphatase 2 scaffold subunit Abeta; PP2A-Aβ/PR65β/PPP2R1B |
| Positive Sample: | Rat spleen |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm |
| Calculated MW: | 52kDa/61kDa/66kDa/73kDa |
| Observed MW: | 66kDa |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
| Purification Method: | Affinity purification |
| Gene ID: | 5519 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from Rat spleen using PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb(CAB24836) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s. |
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