The POU6F1 Polyclonal Antibody (CAB7299) is a valuable tool for researchers studying the POU6F1 protein, a transcription factor involved in the regulation of gene expression. This antibody, generated in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the POU6F1 protein, this antibody allows for the detection and analysis of POU6F1 in various cell types, making it ideal for research in developmental biology and neurobiology.
POU6F1 is a key player in the transcriptional regulation of genes involved in neuronal development and differentiation. Its role in controlling gene expression patterns makes it a crucial target for investigation in studies related to neurodevelopmental disorders and neurodegenerative diseases. Understanding the function of POU6F1 can provide insights into the mechanisms underlying these conditions and may lead to the development of potential therapeutic interventions targeting POU6F1-mediated pathways.
Product Name:
POU6F1 Rabbit Polyclonal Antibody
SKU:
CAB7299
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human POU6F1 (NP_002693.3).
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in actin cytoskeleton and nuclear body.
Purification Method:
Affinity purification
Gene ID:
5463
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using POU6F1 antibody (CAB7299) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.