The POU4F3 Polyclonal Antibody (CAB7712) is a valuable tool for researchers studying POU4F3, a transcription factor known for its role in the development and function of sensory neurons in the inner ear. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds to the POU4F3 protein, allowing for accurate detection and analysis in a variety of cell types, making it ideal for investigations in sensory biology and auditory research.
POU4F3 is essential for the differentiation and maintenance of sensory neurons involved in auditory processing, making it a key player in understanding hearing loss and related disorders. By targeting POU4F3 with this antibody, researchers can gain insight into the molecular mechanisms underlying sensory neuron development and function, offering potential avenues for therapeutic interventions in hearing-related conditions.
Product Name:
POU4F3 Rabbit Polyclonal Antibody
SKU:
CAB7712
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU4F3 (NP_002691.1).
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
Purification Method:
Affinity purification
Gene ID:
5459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of Jurkat cells, using POU4F3 antibody (CAB7712) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
