The POU4F1 Polyclonal Antibody is a powerful tool for research focused on POU4F1, a transcription factor known for its involvement in neuronal development and differentiation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in various applications, including Western blotting.POU4F1, also known as Brn-3a, plays a crucial role in regulating gene expression in neurons and is essential for the development of sensory neurons in the peripheral nervous system. Its dysregulation has been linked to various neurological disorders, making it a key target for studies in neuroscience and neurology.
By using the POU4F1 Polyclonal Antibody, researchers can effectively detect and study POU4F1 protein expression in different cell types, aiding in the advancement of our understanding of neuronal development and function. This antibody is a valuable tool for investigating the role of POU4F1 in neurodevelopmental disorders, neurodegenerative diseases, and other neurological conditions.
Product Name:
POU4F1 Polyclonal Antibody
SKU:
CAB22620
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant protein of human POU4F1.
Tested Applications:
IF/ICCELISA
Recommended Dilution:
IF/ICC,1:50 - 1:200
Synonyms:
BRN3A; RDC-1; ATITHS; Oct-T1; brn-3A
Positive Sample:
Mouse lung,Rat lung
Conjugate:
Unconjugated
Cellular Localization:
cytoplasm, nucleoplasm, nucleus
Calculated MW:
43kDa
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias.
Purification Method:
Affinity purification
Gene ID:
5457
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of A-431 cells using POU4F1Rabbit pAb (CAB22620) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
