The POU3F4 Polyclonal Antibody (CAB17521) is a valuable tool for researchers studying the POU3F4 protein, which is involved in the development and function of the inner ear. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.POU3F4 plays a critical role in the differentiation of hair cells in the cochlea and vestibular system, making it essential for proper auditory and balance function. Dysregulation of POU3F4 has been linked to hearing loss and other inner ear disorders, making it an important target for research in the fields of auditory development and sensory biology.
By using the POU3F4 Polyclonal Antibody, researchers can accurately detect and analyze the expression of POU3F4 in different cell types and tissues, providing valuable insights into its role in inner ear development and function. This antibody is a valuable tool for studies aiming to understand the mechanisms underlying inner ear disorders and potentially develop targeted therapies for hearing-related conditions.
Product Name:
POU3F4 Rabbit Polyclonal Antibody
SKU:
CAB17521
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human POU3F4 (NP_000298.3).
This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.
Purification Method:
Affinity purification
Gene ID:
5456
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293F cells transfected with POU3F4, using POU3F4 Rabbit pAb (CAB17521) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.5s.
