The POU3F2 Polyclonal Antibody (CAB18576) is a highly specific research tool designed for the detection of POU3F2 protein, a transcription factor involved in various biological processes, including embryonic development and cell differentiation. This antibody, produced in rabbits, is particularly suitable for use in immunohistochemistry and Western blot applications, where it demonstrates high specificity and sensitivity in detecting POU3F2 in human samples.POU3F2, also known as Brain-2 (Brn-2), is a key regulator of neural development and has been implicated in neurogenesis, neuronal differentiation, and brain development.
Its expression has been linked to various neurological disorders and brain tumors, making it a valuable target for research aimed at understanding the molecular mechanisms underlying these conditions. The POU3F2 Polyclonal Antibody provides researchers with a reliable tool to investigate the role of POU3F2 in normal development and disease pathology, offering insights that may ultimately lead to the development of novel therapeutic interventions.
Product Name:
POU3F2 Rabbit Polyclonal Antibody
SKU:
CAB18576
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human POU3F2 (NP_005595.2).
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
Purification Method:
Affinity purification
Gene ID:
5454
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using POU3F2 Rabbit pAb (CAB18576) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
