The POU2F2 Polyclonal Antibody is a valuable tool for researchers studying the POU2F2 protein, also known as Oct-2, which plays a crucial role in gene regulation and immune response. This antibody is raised in rabbits and has been validated for use in various applications, including Western blotting and immunohistochemistry.POU2F2 is a transcription factor that regulates the expression of genes involved in immune response and cell differentiation. Its function in B cell development and activation makes it an important target for research in immunology and cancer biology.
This antibody specifically binds to POU2F2, allowing for the detection and analysis of this protein in a variety of cell types and tissues.Researchers studying the role of POU2F2 in immune regulation, lymphoid development, and oncogenesis will find this antibody to be a valuable asset in their experimental work. By understanding the function of POU2F2, we can gain insights into the mechanisms underlying immune-related diseases and potentially identify new therapeutic targets for intervention.
Product Name:
POU2F2 Polyclonal Antibody
SKU:
CAB21297
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence within amino acids 400-479 of human POU2F2 (NP_001193954.1).
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5452
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using POU2F2 antibody (CAB21297) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
