The POU2AF1 Polyclonal Antibody (CAB6696) is a valuable tool for researchers studying POU2AF1, a transcription factor essential for B cell development and function. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the POU2AF1 protein, allowing for accurate detection and analysis in various cell types.POU2AF1, also known as OBF-1, plays a crucial role in the regulation of genes involved in B cell differentiation and activation.
Its involvement in the immune response makes it an important target for research in immunology and cancer. By understanding the function of POU2AF1, researchers can gain insights into the mechanisms underlying B cell development and immune response regulation, leading to potential therapeutic advancements in diseases such as leukemia and lymphoma.
Product Name:
POU2AF1 Rabbit Polyclonal Antibody
SKU:
CAB6696
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-256 of human POU2AF1 (NP_006226.2).
Enables transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex.
Purification Method:
Affinity purification
Gene ID:
5450
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using POU2AF1 Rabbit pAb (CAB6696) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.