POT1 Rabbit Polyclonal Antibody (CAB1491)
- SKU:
- CAB1491
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | POT1 Rabbit Polyclonal Antibody |
SKU: | CAB1491 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2). |
Sequence: | TIHH YGCK QCSS LRSI QNLN SLVD KTSW IPSS VAEA LGIV PLQY VFVM TFTL DDGT GVLE AYLM DSDK FFQI PASE VLMD DDLQ KSVD MIMD MFCP PGIK IDAY PWLE CFIK SYNV TNGT DNQI CYQI FDTT VAED VI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | GLM9; CMM10; HPOT1; POT1 |
Positive Sample: | A-431,HeLa,DU145,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, telomere. |
Calculated MW: | 71kDa |
Observed MW: | 75kDa |
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 25913 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |