The POSTN Polyclonal Antibody (CAB14556) is a high-quality antibody designed for research involving POSTN, a protein associated with tissue repair and remodeling. This antibody, produced in rabbits, is highly specific and sensitive for detecting POSTN in human samples, making it a valuable tool for studies in regenerative medicine and fibrosis research.POSTN, also known as periostin, plays a crucial role in promoting tissue regeneration and remodeling after injury. It is involved in various physiological processes, such as wound healing, bone formation, and cardiac remodeling. Understanding the function and regulation of POSTN is essential for developing novel therapeutic strategies for conditions like heart failure, fibrosis, and tissue damage.
The CAB14556 antibody is validated for use in Western blot applications, allowing for accurate and precise detection of POSTN in different cell types and tissues. Its ability to specifically bind to POSTN makes it a reliable tool for analyzing the expression levels and localization of this protein in various experimental settings. Researchers in the field of tissue repair, fibrosis, and regenerative medicine can benefit from using the POSTN Polyclonal Antibody for their studies.
Product Name:
POSTN Rabbit Polyclonal Antibody
SKU:
CAB14556
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 472-751 of human POSTN (NP_001129408.1).
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
10631
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using POSTN Rabbit pAb (CAB14556) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
