The POSTN Polyclonal Antibody (PAC021510) is an essential tool for researchers studying the POSTN protein, which is involved in various biological processes such as cell adhesion, migration, and tissue repair. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it a reliable choice for Western blot applications. By binding to the POSTN protein, this antibody allows for the detection and analysis of POSTN in different cell types, making it a versatile option for studies in immunology and cancer research.POSTN, also known as periostin, is a key player in tissue remodeling and repair processes.
It is often dysregulated in diseases such as cancer, fibrosis, and cardiovascular disorders, highlighting its importance as a potential therapeutic target. Research into the role of POSTN in these diseases is crucial for the development of new treatment strategies that target the protein's function and activity.Overall, the POSTN Polyclonal Antibody is a valuable tool for researchers looking to delve into the molecular mechanisms of POSTN and its impact on various diseases. Its specificity and reliability make it an asset for studies aiming to uncover new insights into the role of POSTN in health and disease.
Antibody Name:
Postn Antibody (PACO21510)
Antibody SKU:
PACO21510
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Peptide sequence around aa. 125~129( R-E-E-I-E) derived from Mouse Periostin.
Form:
Liquid
Storage Buffer:
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extract from Rat brain and Mouse brain Tissue using Periostin Antibody.
Background:
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. Sugiura T., Takamatsu H., Kudo A., Amann E. Protein Expr. Purif. 6:305-311(1995)
Synonyms:
POSTN; OSF2; OSF-2; PN; osteoblast specific factor
UniProt Protein Function:
POSTN: Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:Secreted, signal peptide; Secreted; Cell adhesion; Motility/polarity/chemotaxis
