The POP7 Polyclonal Antibody (CAB8183) is a valuable tool for researchers studying the POP7 protein, an essential component of the RNase MRP and RNase P complexes involved in RNA processing. This antibody, generated in rabbits, displays high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the POP7 protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies in molecular biology and RNA processing mechanisms.
POP7 is a key player in RNA processing pathways and its dysfunction has been linked to various diseases, including neurodegenerative disorders and cancer. By investigating the function of POP7, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets. The POP7 Polyclonal Antibody provides a reliable tool for studying the role of POP7 in cellular processes, offering new avenues for research and drug development in the field of RNA biology.
Product Name:
POP7 Rabbit Polyclonal Antibody
SKU:
CAB8183
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human POP7 (NP_005828.2).
Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Located in nucleolus. Part of multimeric ribonuclease P complex and ribonuclease MRP complex.
Purification Method:
Affinity purification
Gene ID:
10248
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using POP7 antibody (CAB8183) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
