The POP4 Polyclonal Antibody (CAB4452) is a vital tool for researchers studying the POP4 protein, a key player in RNA processing and gene expression regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the POP4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential asset for studies in molecular biology and genetics.POP4 is an essential component of the RNA processing machinery, involved in cleavage and polyadenylation of mRNA transcripts. Its role in gene expression regulation makes it a crucial target for research into various biological processes, including RNA metabolism, protein synthesis, and cellular differentiation.
By understanding the function of POP4, researchers can gain insights into mechanisms underlying diseases such as cancer, neurodegenerative disorders, and developmental abnormalities.In summary, the POP4 Polyclonal Antibody is a valuable tool for investigating the role of POP4 in gene expression regulation and RNA processing. Its high reactivity and specificity make it an invaluable asset for researchers in the fields of molecular biology, genetics, and cellular biology.
Product Name:
POP4 Rabbit Polyclonal Antibody
SKU:
CAB4452
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human POP4 (NP_006618.1).
This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10775
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using POP4 Rabbit pAb (CAB4452) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
