PON3 Rabbit Polyclonal Antibody (CAB16418)
- SKU:
- CAB16418
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | PON3 Rabbit Polyclonal Antibody |
SKU: | CAB16418 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PON3 (NP_000931.1). |
Sequence: | HDNW DLTQ LKVI QLGT LVDN LTVD PATG DILA GCHP NPMK LLNY NPED PPGS EVLR IQNV LSEK PRVS TVYA NNGS VLQG TSVA SVYH GKIL IGTV FHKT L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PON3 |
Positive Sample: | Jurkat,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular space. |
Calculated MW: | 40kDa |
Observed MW: | 39kDa |
This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized.
Purification Method: | Affinity purification |
Gene ID: | 5446 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |