PON2 Rabbit Polyclonal Antibody (CAB1646)
- SKU:
- CAB1646
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PON2 Rabbit Polyclonal Antibody |
SKU: | CAB1646 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PON2 (NP_000296.2). |
Sequence: | MGRL VAVG LLGI ALAL LGER LLAL RNRL KASR EVES VDLP HCHL IKGI EAGS EDID ILPN GLAF FSVG LKFP GLHS FAPD KPGG ILMM DLKE EKPR AREL RISR GFDL ASFN PHGI STFI DNDD TVYL FVVN HPEF KNTV EIFK FEEA ENSL LHLK TVKH ELLP SVND ITAV GPAH FYAT NDHY FSDP FLKY LETY LNLH WANV VYYS PN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PON2 |
Positive Sample: | HepG2,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Peripheral membrane protein. |
Calculated MW: | 39kDa |
Observed MW: | 37kDa |
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 5445 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |