PON1 Rabbit Polyclonal Antibody (CAB7338)
- SKU:
- CAB7338
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PON1 Rabbit Polyclonal Antibody |
SKU: | CAB7338 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human PON1 (NP_000437.3). |
Sequence: | HQSS YQTR LNAL REVQ PVEL PNCN LVKG IETG SEDL EILP NGLA FISS GLKY PGIK SFNP NSPG KILL MDLN EEDP TVLE LGIT GSKF DVSS FNPH GIST FTDE DNAM YLLV VNHP DAKS TVEL FKFQ EEE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ESA; PON; MVCD5; PON1 |
Positive Sample: | 293T,Jurkat,Mouse thymus,Mouse heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular space. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa/55kDa |
This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7.
Purification Method: | Affinity purification |
Gene ID: | 5444 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |