The POMGNT1 Polyclonal Antibody (CAB9879) is a valuable tool for researchers studying POMGNT1, an enzyme involved in protein glycosylation processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the POMGNT1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it well-suited for investigations in the fields of biochemistry and cell biology.POMGNT1 plays a crucial role in protein modification processes, particularly in the glycosylation of proteins involved in cell signaling and communication.
Dysregulation of POMGNT1 has been linked to various diseases, including muscular dystrophy and neurodevelopmental disorders. Research into the function and regulation of POMGNT1 is vital for understanding these conditions and developing potential therapeutic interventions.Overall, the POMGNT1 Polyclonal Antibody (CAB9879) offers researchers a reliable tool for studying the role of POMGNT1 in cellular processes and disease pathology, ultimately contributing to advancements in the biomedical sciences.
Product Name:
POMGNT1 Rabbit Polyclonal Antibody
SKU:
CAB9879
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 411-660 of human POMGNT1 (NP_060209.3).
Golgi apparatus membrane, Single-pass type II membrane protein.
Calculated MW:
75kDa
Observed MW:
90kDa
This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
55624
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using POMGNT1 antibody (CAB9879) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
