The POLR2L Polyclonal Antibody (CAB2491) is a valuable tool for researchers studying POLR2L, an essential component of the RNA polymerase II complex. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for Western blot applications. By targeting the POLR2L protein, this antibody enables the detection and analysis of POLR2L expression in a variety of cell types, facilitating investigations in molecular biology and gene expression studies.POLR2L is a subunit of RNA polymerase II, the enzyme responsible for transcribing messenger RNA in eukaryotic cells. As a key player in the transcription process, POLR2L is involved in the regulation of gene expression and plays a crucial role in cellular function.
Research on POLR2L can provide insights into mechanisms underlying gene regulation, RNA synthesis, and diseases related to transcriptional dysregulation.By utilizing the POLR2L Polyclonal Antibody, researchers can explore the functions and interactions of POLR2L within the RNA polymerase II complex, shedding light on its roles in cellular processes and disease pathways. This antibody offers a reliable tool for investigating the molecular mechanisms of gene transcription and advancing our understanding of the fundamental processes that govern gene expression.
Product Name:
POLR2L Rabbit Polyclonal Antibody
SKU:
CAB2491
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-67 of human POLR2L (NP_066951.1).
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Purification Method:
Affinity purification
Gene ID:
5441
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using POLR2L Rabbit pAb (CAB2491) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
