POLR2E Rabbit Polyclonal Antibody (CAB1755)
- SKU:
- CAB1755
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | POLR2E Rabbit Polyclonal Antibody |
SKU: | CAB1755 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POLR2E (NP_002686.2). |
Sequence: | MDDE EETY RLWK IRKT IMQL CHDR GYLV TQDE LDQT LEEF KAQF GDKP SEGR PRRT DLTV LVAH NDDP TDQM FVFF PEEP KVGI KTIK VYCQ RMQE ENIT RALI VVQQ GMTP SAKQ SLVD MAPK YILE QFLQ QELL INIT EHEL VPEH VVMT KEEV TELL ARYK LREN QLPR IQAG DPVA RYFG IKRG QVVK IIRP SETA GRYI TYRL VQ |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:100 - 1:500 |
Synonyms: | RPB5; XAP4; RPABC1; hRPB25; hsRPB5; POLR2E |
Positive Sample: | HepG2,U-937,SW620,Raji,Jurkat,SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 25kDa |
Observed MW: | 26kDa |
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5434 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |