POLR2B Rabbit Polyclonal Antibody (CAB5928)
- SKU:
- CAB5928
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | POLR2B Rabbit Polyclonal Antibody |
SKU: | CAB5928 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POLR2B (NP_000929.1). |
Sequence: | MYDA DEDM QYDE DDDE ITPD LWQE ACWI VISS YFDE KGLV RQQL DSFD EFIQ MSVQ RIVE DAPP IDLQ AEAQ HASG EVEE PPRY LLKF EQIY LSKP THWE RDGA PSPM MPNE ARLR NLTY SAPL YVDI TKTV IKEG EEQL QTQH QKTF IGKI PIML RSTY CLLN GLTD RDLC ELNE CPLD PGGY FIIN GSEK VLIA QEKM ATNT VYVF AKKD SKYA YTGE CRSC LENS SRPT STIW VSML ARGG QGAK KSAI GQRI VATL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | RPB2; POL2RB; hRPB140; POLR2B |
Positive Sample: | SH-SY5Y,A375,HepG2,BT-474,Mouse brain,Mouse spleen,Mouse ovary,Rat ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 134kDa |
Observed MW: | 134kDa |
This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5431 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |