POLK Rabbit Polyclonal Antibody (CAB12052)
- SKU:
- CAB12052
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | POLK Rabbit Polyclonal Antibody |
SKU: | CAB12052 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human POLK (NP_057302.1). |
Sequence: | MDST KEKC DSYK DDLL LRMG LNDN KAGM EGLD KEKI NKII MEAT KGSR FYGN ELKK EKQV NQRI ENMM QQKA QITS QQLR KAQL QVDR FAME LEQS RNLS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DINP; POLQ; DINB1; POLK |
Positive Sample: | 22RV1,SKOV3,U-87MG,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 99kDa |
Observed MW: | 71kDa |
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients.
Purification Method: | Affinity purification |
Gene ID: | 51426 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |