POLG2 Rabbit Polyclonal Antibody (CAB6695)
- SKU:
- CAB6695
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | POLG2 Rabbit Polyclonal Antibody |
SKU: | CAB6695 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of human POLG2 (NP_009146.2). |
Sequence: | HPVF DTKQ IRNG VKSI GEKT EASL VWFT PPRT SNQW LDFW LRHR LQWW RKFA MSPS NFSS SDCQ DEEG RKGN KLYY NFPW GKEL IETL WNLG DHEL LHMY PGNV SKLH GRDG RKNV VPCV LSVN GDLD RGML AYLY DSFQ LTEN SFTR KKNL HRKV LKLH PCLA PIKV ALDV GRGP TLEL RQVC QGLF NELL ENGI SVWP GYLE TMQS SLEQ LYSK YDEM SILF TVLV TETT LENG LIHL RSRD TTMK EMMH ISKL KDFL IKYI SSAK NV |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:10 - 1:100 |
Synonyms: | HP55; POLB; PEOA4; POLGB; MTPOLB; MTDPS16; MTDPS16A; MTDPS16B; POLG-BETA; POLG2 |
Positive Sample: | 293T,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Purification Method: | Affinity purification |
Gene ID: | 11232 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |