The POLDIP2 Polyclonal Antibody (CAB15812) is a valuable tool for researchers studying POLDIP2, a protein involved in regulating cell growth and metabolism. This antibody, produced in rabbits, is specifically designed for use with human samples and has been validated for Western blot applications. By binding to the POLDIP2 protein, this antibody allows for the detection and analysis of POLDIP2 in various cell types, making it an essential tool for studies in molecular biology and cancer research.
POLDIP2, also known as polymerase delta interacting protein 2, plays a crucial role in DNA replication and repair processes, making it a key player in maintaining genomic stability. Dysregulation of POLDIP2 has been implicated in various diseases, including cancer and metabolic disorders. By understanding the function and regulation of POLDIP2, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets.
Product Name:
POLDIP2 Rabbit Polyclonal Antibody
SKU:
CAB15812
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human POLDIP2 (NP_056399.1).
This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
26073
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using POLDIP2 Rabbit pAb (CAB15812) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
