POLD2 Rabbit Polyclonal Antibody (CAB6834)
- SKU:
- CAB6834
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | POLD2 Rabbit Polyclonal Antibody |
SKU: | CAB6834 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-360 of human POLD2 (NP_006221.2). |
Sequence: | LQPE EKCC VVGT LFKA MPLQ PSIL REVS EEHN LLPQ PPRS KYIH PDDE LVLE DELQ RIKL KGTI DVSK LVTG TVLA VFGS VRDD GKFL VEDY CFAD LAPQ KPAP PLDT DRFV LLVS GLGL GGGG GESL LGTQ LLVD VVTG QLGD EGEQ CSAA HVSR VILA GNLL SHST QSRD SINK AKYL TKKT QAAS VEAV KMLD EILL QLSA SVPV DVMP GEFD PTNY TLPQ QPLH PCMF PLAT AYST L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | POLD2 |
Positive Sample: | HeLa,HL-60,HepG2,BT-474,NCI-H460,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Purification Method: | Affinity purification |
Gene ID: | 5425 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |