[KO Validated] DNA Polymerase beta Rabbit Polyclonal Antibody (CAB1681)
The KO Validated DNA Polymerase Beta Polyclonal Antibody (CAB1681) is a valuable tool for researchers studying DNA polymerase beta, an enzyme involved in DNA repair and replication processes. This polyclonal antibody, produced in rabbits, is highly specific for detecting DNA polymerase beta in a variety of samples and has been validated for use in Western blot applications.DNA polymerase beta plays a crucial role in maintaining genomic stability by repairing damaged DNA and ensuring accurate replication during cell division. Dysregulation of this enzyme has been implicated in various diseases, including cancer and neurodegenerative disorders.
By using the KO Validated DNA Polymerase Beta Polyclonal Antibody, researchers can accurately assess the levels and activity of DNA polymerase beta in different cell types, aiding in the investigation of its function in normal and diseased states.This antibody is an essential tool for scientists studying DNA repair mechanisms, genetic mutations, and the development of potential therapeutics targeting DNA polymerase beta. Its high specificity and reliability make it a valuable asset for research in molecular biology, oncology, and genetics.
Product Name:
[KO Validated] DNA Polymerase beta Rabbit Polyclonal Antibody
SKU:
CAB1681
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human DNA Polymerase beta (NP_002681.1).
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
Purification Method:
Affinity purification
Gene ID:
5423
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] DNA Polymerase beta Rabbit pAb (CAB1681) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
