POGLUT1 Rabbit Polyclonal Antibody (CAB17737)
- SKU:
- CAB17737
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | POGLUT1 Rabbit Polyclonal Antibody |
SKU: | CAB17737 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1). |
Sequence: | MYPA WTFW EGGP AVWP IYPT GLGR WDLF REDL VRSA AQWP WKKK NSTA YFRG SRTS PERD PLIL LSRK NPKL VDAE YTKN QAWK SMKD TLGK PAAK DVHL VDHC KYKY LFNF RGVA ASFR F |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | Rumi; CLP46; MDSRP; C3orf9; KTELC1; LGMD2Z; MDS010; hCLP46; KDELCL1; LGMDR21; POGLUT1 |
Positive Sample: | Mouse spleen,Mouse lung,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum, endoplasmic reticulum lumen |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 56983 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |