The PODXL2 Polyclonal Antibody (PACO07211) is a valuable tool for researchers studying PODXL2, a cell surface protein involved in various cellular processes, including cell adhesion and signaling. This antibody, generated in rabbits, shows high specificity and sensitivity towards human samples, making it suitable for a range of applications such as Western blotting.PODXL2, also known as podocalyxin-like protein 2, has been implicated in cancer progression and metastasis, making it a promising target for cancer research. By targeting PODXL2 with this antibody, researchers can gain insights into its role in tumor biology and potentially develop targeted therapies for cancer treatment.
The ability of the PACO07211 antibody to specifically detect PODXL2 in various cell types makes it a valuable tool for researchers in the fields of oncology, cell biology, and immunology. By studying the expression and function of PODXL2, researchers can further our understanding of its role in disease progression and potentially uncover new therapeutic targets.
Antibody Name:
PODXL2 Antibody (PACO07211)
Antibody SKU:
PACO07211
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human Endoglycan.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of Hela using Endoglycan antibody. Secondary antibody was diluted at 1:20000.
Synonyms:
PODXL2; Podocalyxin-like protein 2; Endoglycan
UniProt Protein Function:
PODXL2: Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L- selectins. Belongs to the podocalyxin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Cell adhesionChromosomal Location of Human Ortholog: 3q21.3Cellular Component: integral to plasma membraneMolecular Function: glycosaminoglycan binding; protein bindingBiological Process: leukocyte tethering or rolling
UniProt Protein Details:
NCBI Summary:
This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012]
