The PNRc2 Polyclonal Antibody (CAB16549) is a powerful tool for researchers studying PNRc2, a protein involved in RNA splicing and gene expression regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards PNRc2 in human samples, making it ideal for Western blot applications. By binding to PNRc2, this antibody enables accurate detection and analysis of the protein in various cell types, offering valuable insights into its function in molecular biology and cancer research.PNRc2, also known as polyribonucleotide nucleotidyltransferase 2, plays a critical role in RNA processing and mRNA quality control, making it a key player in gene expression regulation.
Its involvement in these processes underscores its relevance in diseases such as cancer, where dysregulation of gene expression can drive abnormal cell growth and proliferation. By studying PNRc2, researchers can gain a better understanding of its role in cancer development and potentially identify novel therapeutic targets for intervention.
Product Name:
PNRC2 Rabbit Polyclonal Antibody
SKU:
CAB16549
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PNRC2 (NP_060231.1).
Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in Golgi apparatus; P-body; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
55629
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using PNRC2 Rabbit pAb (CAB16549) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
