PNPT1 Rabbit Polyclonal Antibody (CAB11676)
- SKU:
- CAB11676
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PNPT1 Rabbit Polyclonal Antibody |
SKU: | CAB11676 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PNPT1 (NP_149100.2). |
Sequence: | MAAC RYCC SCLR LRPL SDGP FLLP RRDR ALTQ LQVR ALWS SAGS RAVA VDLG NRKL EISS GKLA RFAD GSAV VQSG DTAV MVTA VSKT KPSP SQFM PLVV DYRQ KAAA AGRI PTNY LRRE IGTS DKEI LTSR IIDR SIRP LFPA GYFY DTQV LCNL LAVD GVNE PDVL AING ASVA LSLS DIPW NGPV GAVR IGII DGEY VVNP TRKE MSSS TLNL VVAG APKS QIVM LEAS AENI LQQD FCHA IKVG VKYT QQII QGIQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OLD35; SCA25; DFNB70; PNPASE; old-35; COXPD13; PNPT1 |
Positive Sample: | HeLa,293T,B cells |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Mitochondrion intermembrane space, Peripheral membrane protein. |
Calculated MW: | 86kDa |
Observed MW: | 110kDa |
The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.
Purification Method: | Affinity purification |
Gene ID: | 87178 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |