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PNPLA2 Monoclonal Antibody [PAT18E6AT] (CPAB0669)

SKU:
CPAB0669
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT18E6AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

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PNPLA2 Monoclonal Antibody [PAT18E6AT] (CPAB0669)

The PNPLA2 Polyclonal Antibody (CPAB0669) is a valuable tool for researchers studying PNPLA2, a key enzyme involved in lipid metabolism and cellular homeostasis. Raised in rabbits, this antibody has high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PNPLA2 protein, this antibody allows for the detection and analysis of PNPLA2 in a variety of cell types, making it ideal for studies in lipid metabolism, obesity, and metabolic disorders.PNPLA2, also known as adipose triglyceride lipase (ATGL), plays a crucial role in the breakdown of triglycerides in adipose tissue and is involved in the regulation of energy balance and lipid storage.

Dysregulation of PNPLA2 activity has been linked to metabolic disorders such as obesity, insulin resistance, and fatty liver disease, making it a promising target for therapeutic interventions. By studying the function of PNPLA2, researchers can gain insights into the underlying mechanisms of these diseases and develop new treatments targeting lipid metabolism.Overall, the PNPLA2 Polyclonal Antibody (CPAB0069) is a reliable tool for investigating the role of PNPLA2 in lipid metabolism and metabolic disorders, providing valuable insights for the development of novel therapies targeting these pathways.

Product Name:PNPLA2 Antibody
Product Sku:CPAB0669
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PNPLA2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PNPLA2 protein 3-54 amino acids purified from Ecoli.
Clone:PAT18E6AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:PNPLA2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:PNPLA2 is an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in the PNPLA2 gene are linked to neutral lipid storage disease with myopathy.
Synonyms:Patatin-like phospholipase domain-containing protein 2, Adipose triglyceride lipase, Desnutrin Transport-secretion protein 2, TTS2.2, Calcium-independent phospholipase A2, IPLA2-zeta Pigment epithelium-derived factor, TTS2, PNPLA2, ATGL, PEDF-R, FP17548, TTS-2.2, DKFZp667M109, 1110001C14Rik.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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